Read a selection of our recent peer-reviewed publications covering the lifespan of the NIHR Newcastle MIC.

2023

Patient Self-Testing of Kidney Function at Home, a Prospective Clinical Feasibility Study in Kidney Transplant Recipients

Murray JS, Williams CJ, Lendrem C, Smithson J, Allinson C, Robinson J, et al. Kidney International Reports. 2023; in press.

2022

Perceived feasibility, facilitators and barriers to incorporating point-of-care testing for SARS-CoV-2 into emergency medical services by ambulance service staff: a survey-based approach

Green K, Micocci M, Hicks T, Winter A, Martin JE, Shinkins B, et al. BMJ Open. 2022; 12:e064038.

Risks of infection, hospital and ICU admission, and death from COVID-19 in people with asthma: systematic review and meta-analyses.

Otunla A, Rees K, Dennison P, Hobbs R, Suklan J, Schofield E et al. BMJ Evidence-Based Medicine. 2022; 27:263-273.

Clinicians’ Perspectives on Barriers and Facilitators for the Adoption of Non-Invasive Liver Tests for NAFLD: A Mixed-Method Study.

Vali Y, Eijk R, Hicks T, Jones WS, Suklan J, Holleboom AG, et al.  J Clin Med. 2022; 11(10):2707.

Bayesian sample size determination for diagnostic accuracy studies.

Wilson KJ, Williamson SF, Allen AJ, Williams CJ, Hellyer TP, Lendrem BC.  Statistics in Medicine. 2022;1-15.

Diagnosing ventilator-associated pneumonia (VAP) in UK NHS ICUs: the perceived value and role of a novel optical technology.

Jones WS, Suklan J, Winter A, Green K, Craven T, Bruce A, et al. Diagn Progn Res. 2022; 6(1):5.

Primary Sjögren’s syndrome: longitudinal real-world, observational data on health-related quality of life.

Tarn J, Lendrem D, McMeekin P, Lendrem C, Hargreaves B, Ng W-F. J Intern Med. 2022; 00 1- 7.

Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma.

Newman A, Zaka M, Zhou P, Blain A, Erhorn A, Barnard A, et al. Leukemia. 2022; 36:781–789.

2021

Strategies to implement SARS-CoV-2 point-of-care testing into primary care settings: a qualitative secondary analysis guided by the Behaviour Change Wheel.

Kierkegaard P, Hicks T, Allen AJ, Yang Y, Hayward G, Glogowska M, Nicholson BD et al. Implement Sci Commun. 2021; 2:139.

Systematic review of studies investigating ventilator associated pneumonia diagnostics in intensive care.

Al‑Omari B, McMeekin P, Allen AJ, Akram AR, Graziadio S, Suklan J, Jones WS, et al. BMC Pulm Med. 2021; 21:196.

 Care pathway and prioritization of rapid testing for COVID-19 in UK hospitals: a qualitative evaluation.

Hicks T, Winter A, Green K, Kierkegaard P, Price DA, Body R, Allen AJ, et al. BMC Health Serv Res. 2021; 21:532.

Purines for Rapid Identification of Stroke Mimics (PRISM): study protocol for a diagnostic accuracy study.

Shaw L, Graziadio S, Lendrem C, Dale N, Ford GA, Roffe C, Smith CJ, et al. Diagn Progn Res. 2021. 5:11.

Conducting invasive urodynamics in primary care: qualitative interview study examining experiences of patients and healthcare professionals.

Milosevic S, Joseph-Williams N, Pell B, Cain E, Hackett R, Murdoch F, Ahmed H, Allen AJ et al. Diagn Progn Res. 2021; 5:10.

Utility of Routine Laboratory Biomarkers to Detect COVID-19: A Systematic Review and Meta-Analysis.

Suklan J, Cheaveau J, Hill S, Urwin SG, Green K, Winter A, Hicks T, et al. Viruses. 2021; 13(5):803.

Is Point-of-Care testing feasible and safe in care homes in England? An exploratory usability and accuracy evaluation of a Point-of-Care Polymerase Chain Reaction test for SARS-COV-2.

Micocci M, Gordon AL, Seo MK, Allen AJ, Davies K, Lasserson D, Thompson C, et al. Age and Ageing. 2021; afab072.

Improving the identification of patients with a genetic diagnosis of familial hypercholesterolaemia in primary care: A strategy to achieve the NHS long term plan.

Ingoe L, Potter A, Musson S, Neely D, Pilkington G, Allen AJ, Reay D, et al. Atherosclerosis. 2021; 321: 38-45.

Comparative diagnostic accuracy studies with an imperfect reference standard – a comparison of correction methods.

Umemneku Chikere, C.M., Wilson, K.J., Allen, A.J. et al. BMC Med Res Methodol. 2021; 21: 67.

COVID-19 testing in English care homes and implications for staff and residents.

Micocci M, Gordon AL, Allen AJ, Hicks T, Kierkegaard P, McLister A, Walne S et al. Age and Ageing. 2021; afab015.

2020

Predicting Postoperative Vision for Macular Hole with Automated Image Analysis.

Murphy DC, Nasrulloh AV, Lendrem C, Graziado S, Alberti M, la Cour M, Obara B, Steel DHW. Ophthalmol Retina. 2020;4(12):1211-1213.

At what times during infection is SARS-CoV-2 detectable and no longer detectable using RT-PCR-based tests? A systematic review of individual participant data.

Mallett S, Allen AJ, Graziadio S, Taylor SA, Sakai NS, Green K, Suklan J et al. BMC Med. 2020 18(1):346.

Asthma and COVID-19: review of evidence on risks and management considerations.

Hartmann-Boyce J, Gunnell J, Drake J, Otunla A, Suklan J, Schofield E, Kinton J, et al. BMJ Evidence-Based Medicine. 2020.,

Unmet clinical needs for COVID-19 tests in UK health and social care settings.

Graziadio S, Urwin SG, Cocco P, Micocci M, Winter A, Yang Y, Price DA, Messenger M, Allen AJ, Shinkins B, CONDOR Steering group. PLoS One. 2020 15(11):e0242125.

The Clinical Need for New Diagnostics in the Identification and Management of Patients with Suspected Sepsis in UK NHS Hospitals: A Survey of Healthcare Professionals.

Winter A, Jones WS, Allen AJ, Price DA, Rostron A, Filieri R, Graziadio S. Antibiotics (Basel). 2020;9(11):737.

Cost Consequences for the NHS of Using a Two-Step Testing Method for the Detection of Clostridium difficile with a Point of Care, Polymerase Chain Reaction Test as the First Step.

Jones WS, Rice S, Power HM, Maniatopoulos G, Suklan J, Beyer F, Wilcox MH et al. Diagnostics (Basel). 2020;10(10):819.

Diagnostic and economic evaluation of a point-of-care test for respiratory syncytial virus.

Allen AJ, Gonzalez-Ciscar A, Lendrem C, Suklan J, Allen K, Bell A, Baxter F, et al. ERJ Open Res. 2020;6(3):00018-2020.

PRImary care Management of lower Urinary tract Symptoms in men: protocol for development and validation of a diagnostic and clinical decision support tool (the PriMUS study).

Pell B, Thomas-Jones E, Bray A, Agarwal R, Ahmed H, Allen AJ, Clarke S, et al. BMJ Open. 2020;10(6):e037634.

First experience of COVID-19 screening of health-care workers in England.

Hunter E, Price DA, Murphy E, van der Loeff IS, Baker KF, Lendrem D, Lendrem C, et al. Lancet. 2020;395(10234):e77-e78.

Asymmetrical Bioimpedance in the Anterior Circulation for Urgent Stratification of suspected Stroke (ABACUS Stroke): study protocol for a diagnostic accuracy study.

Price CI, Shaw L, Dixit A, Graziadio S, Lendrem C, Mitra D, Rodgers H, Sutcliffe L, White P. Diagn Progn Res. 2020;4(2).

How to Ease the Pain of Taking a Diagnostic Point of Care Test to the Market: A Framework for Evidence Development.

Graziadio S, Winter A, Lendrem BC, Suklan J, Jones WS, Urwin SG, O’Leary RA, et al. Micromachines (Basel). 2020;11(3):291

High Variability in Sepsis Guidelines in UK: Why Does It Matter?

Bray A, Kampouraki E, Winter A, Jesuthasan A, Messer B, Graziadio S. Int J Environ Res Public Health. 2020;17(6):2026.

2019

Efficiency and Health Economic Evaluations of BD OneFlow™ Flow Cytometry Reagents for Diagnosing Chronic Lymphoid Leukemia.

Moloney E, Watson H, Barge D, Allen AJ, Carey P, Hislop J, Johnston L, et al. Cytometry B Clin Cytom. 2019;96(6):514-520.

A PCR-based diagnostic testing strategy to identify carbapenemase-producing Enterobacteriaceae carriers upon admission to UK hospitals: early economic modelling to assess costs and consequences.

Moloney E, Lee KW, Craig D, Allen AJ, Graziadio S, Power M, Steeds C. Diagn Progn Res. 2019;3:8.

Opportunities and challenges of a novel cardiac output response to stress (CORS) test to enhance diagnosis of heart failure in primary care: qualitative study.

Charman S, Okwose N, Maniatopoulos G, Graziadio S, Metzler T, Banks H, Vale L, et al. BMJ Open. 2019;9(4):e028122.

Application of MR-ProADM to predict prevention of hospitalisation, derived from a multi-centre study.

Cullinan M, Graziadio S, Price DA. Crit Care. 2019;23(1):129.

Can mid-regional pro-adrenomedullin (MR-proADM) increase the prognostic accuracy of NEWS in predicting deterioration in patients admitted to hospital with mild to moderately severe illness? A prospective single-centre observational study.

Graziadio S, O’Leary RA, Stocken DD, Power M, Allen AJ, Simpson AJ, Price DA. BMJ Open. 2019;8(11):e020337.

Between a ROC and a hard place: Teaching prevalence plots to understand real world biomarker performance in the clinic.

Lendrem BC, Lendrem DW, Pratt AG, Naamane N, McMeekin P, Ng WF, Allen AJ, Power M, Isaacs JD. Pharm Stat. 2019;18(6):632-635.

Diagnostic test evaluation methodology: A systematic review of methods employed to evaluate diagnostic tests in the absence of gold standard – An update.

Umemneku Chikere CM, Wilson K, Graziadio S, Vale L, Allen AJ. PLoS One. 2019; 14(10):e0223832.

Early Economic Evaluation of Diagnostic Technologies: Experiences of the NIHR Diagnostic Evidence Co-operatives.

Abel L, Shinkins B, Smith A, Sutton AJ, Sagoo GS, Uchegbu I, Allen AJ, Graziadio S, Moloney E, Yang Y, Hall P. Med Decis Making. 2019;39(7):857-866.

2018

Cost implications for the NHS of using the Alere™ i Influenza A & B near patient test with nasal swabs.

Allen AJ, O’Leary RA, Davis S, Graziadio S, Jones WS, Simpson AJ, Price DA, Vale L, Power M. Diagn Progn Res. 2018;2:15.

Diagnostic accuracy and cost analysis of the Alere™ i Influenza A&B near-patient test using throat swabs.

Davis S, Allen AJ, O’Leary R, Power M, Price DA, Simpson AJ, Tunbridge A, Vale L, Whiteside M, Evans C, Raza M. J Hosp Infect. 2017;97(3):301-309.

Interactive visualisation for interpreting diagnostic test accuracy study results.

Fanshawe TR, Power M, Graziadio S, Ordóñez-Mena JM, Simpson J, Allen J. BMJ Evid Based Med. 2018;23(1):13-16.